Atherosclerosis: Foam Cell Macrophages

Rubber Ducky, you're the one. 

Pathogenesis of atherosclerosis: when monocytes differentiate into macrophages in the subendothelial wall of arteries, exogenous cholesterol from abnormal lipoproteins enter the cell via surface molecules called scavenger receptors.  

These scavenger receptors may include the molecules CD36 and SRA. 

Once the cholesterol is in the macrophage and stored as droplets, the cell is considered a foam cell.