Poisoned, shot four times, beaten, and drowned. |
But on a more relevant note, Rasputin was also known for his role as the "healer" of Alexei Nikolaevich, Tsarevich of Russia. Alexei suffered from hemophilia, which is a bleeding disorder. In fact, a couple of royal descendants of Queen Victoria were hemophiliacs (oh those silly inbreeders, not that I'm judging). There are a variety of hemophilia disorders, but the two types of most significance are hemophilias A and B.
Hemophilia A (the most common hemophilia) is an X-linked recessive disorder resulting in a deficiency of Factor VIII in the coagulation cascade.
Hemophilia B is an X-linked recessive disorder resulting in a deficiency of Factor IX in the coagulation cascade. The deficiencies in factors VIII and IX will contribute to ineffective formation of fibrin (= ineffective clotting).
Note that a common complication of hemophilia is hemophilic arthropathy, where there is bleeding in the joints that may result in joint deformities if left untreated.
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