Monday, September 27, 2010

Granulocyte Development: Band Forms

Who remembers Planter's Cheez Balls?
Band forms: these are the cells that are one step away from differentiating into neutrophils. Compared to neutrophils (which typically have a multi-lobed nucleus), band forms have a nucleus that is more horse-shoe shaped. (I think they look more cashew/peanut shaped though, hence the Planter's peanuts nucleus). Band forms may increase in the presence of an infection. 

The development of granulocytes (note that they all contain granules!) follows this order:

Myeloblasts
Promyelocytes
Myelocytes
Metamyelocyte
Band form
Neutrophil

A mnemonic for granulocyte development: Mother, Please Make My Bed.

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